An interesting effect of sodium nitroprusside
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چکیده
منابع مشابه
Sodium Nitroprusside Injection
Except when used briefly or at low (< 2 mcg/kg/min) infus ion rates , sodium nitropruss ide gives rise to important quantities of cyanide ion, which can reach toxic, potentially lethal levels (see WARNINGS). The usual dose rate is 0.5 to 10 mcg/kg/min, but infus ion at the maximum dose rate should never las t more than 10 minutes . If blood pressure has not been adequately controlled after 10 m...
متن کاملEffect of sodium nitroprusside-induced hypotension on pulmonary deadspace.
Deliberate hypotension with nitroprusside produced a 40% reduction in mean arterial pressure, but it did not cause any change in the pulmonary deadspace to tidal volume ratio ( Vb/ Vr). This was achieved by adequate hydration both before and during hypotension, as indicated by constant filling pressures. Thus we have shown that deliberate hypotension per se does not increase Vb/ VT, and that va...
متن کاملAccentuated hypotensive effect of sodium nitroprusside in man after captopril.
1. The effects of graded intravenous infusions of sodium nitroprusside on resting blood pressure and heart rate and on the reflex changes in these variables evoked by a standardized Valsalva manoeuvre were studied in six normal subjects. The effects of nitroprusskle on the above variables were also studied after pretreatment with captopril, to allow assessment of the role of angiotensin 11. 2. ...
متن کاملDeliberately Lowering Blood Pressure with Sodium Nitroprusside
The goal of hyptensive anesthesia is the safe reduction of intraoperative blood loss, thus reducing transfusion risks. Previous hypotensive technics had a narrow margin of safety in that cardiac output was usually reduced in proportion to the degree of induced hypotension. This is in contrast to the results of our study, in which Sodium Nitroprusside was used as the sole hypotensive agent. Ni...
متن کاملSodium nitroprusside: theory and practice.
Sodium nitroprusside, by a peripheral vasodilator action, is a powerful hypotensive drug. In contrast to established agents, its hypotensive action is accompanied by an unchanged or augmented cardiac output. Intravenous administration of sodium nitroprusside rapidly produces a profound and controllable hypotension. Normotension is swiftly restored by ceasing to infuse the agent, and antidotes a...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1985
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1985.tb10618.x